上海圻明生物科技有限公司

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上海圻明生物科技有限公司

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公司新闻/正文

Phospho-Histone H1.3/Histone H1.4 (Thr17)兔单抗

人阅读 发布时间:2022-06-27 09:06

来源 用途 交叉反应性 分子量
Rabbit WB, IF, IHC, ICC H, M, R 30.0kDa

WB, Western blot; IP, Immunoprecipitation; IF, Immunofluorescence; IHC, Immunohistochemistry; ICC, Immunocytochemistry; FC, Flow Cytometry; ELISA, Enzyme-linked Immunosorbent Assay; ChIP, Chromatin Immunoprecipitation Assay.
H, Human; M, Mouse; R, Rat; C, Chicken; Cw, Cow; Dg, Dog; Gp, Guinea pig; Hm, Hamster; Hr, Horse; Mk, Monkey; Pg, Pig; Rb, Rabbit; S, Sheep; Z, Zebrafish; All, all species expected.
配套提供了Western一抗稀释液,可以用于Western检测或其它适当用途时的一抗稀释。
建议抗体使用时的稀释比例如下(实际使用时需根据抗原水平的高低作适当调整):

WB IP IF IHC ICC FC ELISA ChIP
1:500-1:1,000 - 1:50-1:200 1:50-1:200 1:50-1:200 - - -

抗体详细信息如下:

About this Antibody
Name Phospho-Histone H1.3/Histone H1.4 (Thr17) Rabbit Monoclonal Antibody
Category Rabbit Monoclonal Antibody (RabMAb); Primary antibody
Isotype IgG
Purification Affinity purification
About the Immunogen
Immunogen Recombinant protein
Gene ID 3008/3007(Human); 50709/14957(Mouse); 201097(Rat)
SwissProt P10412/P16402(Human); P43274/P43277(Mouse)
Synonyms H10; H1FV
Category Epigenetics
Background Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

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Phospho-Histone H2A.X (Ser139)兔单抗

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CD9兔单抗

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